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New Insights into Chemical Impact on Aquatic Life

7th October 2024

Our recent research has provided valuable insights into the long-term effects of the fungicide azoxystrobin on aquatic organisms, specifically Ceriodaphnia dubia. This study underscores the importance of advanced modelling techniques in environmental risk assessment.

Study Overview
The research focused on understanding the chronic effects of azoxystrobin, a widely used fungicide, on Ceriodaphnia dubia. By employing Toxicokinetic-Toxicodynamic (TKTD) modelling, the study aimed to predict the chemical’s impact over various timeframes with greater accuracy.

Key Findings

  • Chronic Chemical Impact: The study examined both immediate and prolonged effects of azoxystrobin on the test organisms.
  • Advanced TKTD Modelling: The use of TKTD models allowed for a detailed analysis of how azoxystrobin impacts the organism life-history traits.
  • Predictions with Real-World Scenarios: The models were used to predict real-world exposure scenarios.
  • Enhanced Risk Assessment: The findings aim to refine environmental risk assessments, making them more precise and reliable for regulatory purposes.

Significance
This research represents a significant advancement in our understanding of how chemicals affect aquatic life over time. By improving the accuracy of environmental risk assessments, we can develop better guidelines for the safe use of chemicals, ultimately protecting aquatic ecosystems and human health.

For more detailed information, please refer to the full study published in Environmental Toxicology and Chemistry.

 

Romoli, C., Trijau, M., Muller, E.B., Zakharova, L., Kuhl, R., Coors, A., Sherborne, N., Goussen, B. and Ashauer, R. (2024), Environmental Risk Assessment of Time-Variable Toxicant Exposure with Toxicokinetic–Toxicodynamic Modeling of Sublethal Endpoints and Moving Time Windows: A Case Study with Ceriodaphnia dubia. Environ Toxicol Chem.
https://doi.org/10.1002/etc.5975